Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Polygonummultiflorum

Chunyu Li, Ming Niu, Zhaofang Bai, Congen Zhang, Yanling Zhao, Ruiyu Li, Can Tu, Huifang Li, Jing Jing, Yakun Meng, Zhijie Ma, Wuwen Feng, Jinfa Tang, Yun Zhu, Jinjie Li, Xiaoya Shang, Zhengsheng Zou, Xiaohe Xiao, Jiabo Wang

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 253-265 doi: 10.1007/s11684-017-0508-9

Keywords： Polygonum multiflorum     idiosyncratic hepatotoxicity     metabolomics     stilbene     cis-transisomerization    

Evidence chain-based causality identification in herb-induced liver injury: exemplification of a well-known liver-restorative herb

Jiabo Wang,Zhijie Ma,Ming Niu,Yun Zhu,Qingsheng Liang,Yanling Zhao,Jingyuan Song,Zhaofang Bai,Yaming Zhang,Ping Zhang,Na Li,Yakun Meng,Qi Li,Lushan Qin,Guangju Teng,Junling Cao,Baosen Li,Shilin Chen,Yonggang Li,Zhengsheng Zou,Honghao Zhou,Xiaohe Xiao

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 457-467 doi: 10.1007/s11684-015-0417-8

Keywords： drug-induced liver injury     pharmacognosy     metabolomics     stilbene     Polygonum multiflorum     Chinese herbal